منابع مشابه
Genetic control of testis development.
Sex determination refers to the decision of the bipotential early gonads to develop as either testes or ovaries during embryogenesis. In mammals, a single genetic trigger involved in this pivotal decision has been identified on the Y chromosome: the testis-determining gene SRY/Sry. During embryogenesis, SRY triggers the differentiation of Sertoli cells from the supporting cell precursor lineage...
متن کاملEndocrine disruptors and testis development.
After serving on a panel convened by the U.S. EPA on epidemiological studies needed for evaluation of possible health risks of MTBE as a fuel additive, I feel that the article is quite informative and will no doubt be useful for those contemplating further use of oxygenated fuels. There are two matters that I feel are of some importance , and about them the article is silent. First, the report ...
متن کاملEmbryonic Development of the Testis
Testicular development is a very interesting aspect of male reproduction and fertility. The primordial germ cells migrate from yolk sac to the genital ridge along the wall of the hindgut and the dorsal mesentery to ultimately settle in the genital ridge that would give rise to testes. Sex-determining region of the Y chromosome (SRY) is the principal driver of testes development. Testes developm...
متن کاملGonad development: Assembling the mammalian testis
Mammalian primordial germ cells migrate into gonads of either sex indiscriminately and may be functional even across a species barrier; but certain somatic cell lineages are attracted specifically into the male gonad and are absolutely required for the construction of the seminiferous cords of the testis.
متن کاملHypoxia alters testis development in neonatal rats.
OBJECTIVE To investigate the effects of continued hypoxia on postnatal development of the rat testis. DESIGN Wistar rats were exposed to simulated hypoxia from birth to postnatal day (PND) 45. Testosterone (T) in the plasma and the testis was measured in rats at PND 3, 7, 14, 21, 28, 35 and 45 respectively. Testis histology and cellular ultrastructure were studied. RESULTS a) Hypoxia induce...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Endocrine Reviews
سال: 2018
ISSN: 0163-769X,1945-7189
DOI: 10.1210/er.2018-00140